Hsp27 inhibits IKKβ‐induced NF‐κΕ activity and skeletal muscle atrophy

ABSTRACT Heat shock protein 25/27 (Hsp25/27) is a cytoprotective protein that is ubiquitously expressed in most cells, and is up‐regulated in response to cellular stress. Previous work, in nonmuscle cells, has shown that Hsp27 inhibits TNF‐α‐induced NF‐κB activation. During skeletal muscle disuse, H...

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Veröffentlicht in:	The FASEB journal 2009-10, Vol.23 (10), p.3415-3423
Hauptverfasser:	Dodd, Stephen L., Hain, Brian, Senf, Sarah M., Judge, Andrew R.
Format:	Artikel
Sprache:	eng
Schlagworte:	atrogin-1/MAFbx immobilization MuRFl
Online-Zugang:	Volltext
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