Targeted Loss of Androgen Receptor Signaling in Murine Granulosa Cells of Preantral and Antral Follicles Causes Female Subfertility1

Ovarian granulosa cells display strong androgen receptor (AR) expression, suggesting a functional role for direct AR-mediated actions within developing mammalian follicles. By crossing AR-floxed and anti-Müllerian hormone (AMH)-Cre recombinase mice, we generated granulosa cell-specific androgen rece...

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Veröffentlicht in:	Biology of reproduction 2012-12, Vol.87 (6)
Hauptverfasser:	Walters, Kirsty A, Middleton, Linda J, Joseph, Shai R, Hazra, Rasmani, Jimenez, Mark, Simanainen, Ulla, Allan, Charles M, Handelsman, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	androgen receptor female reproduction granulosa cell ovarian function
Online-Zugang:	Volltext
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