Preimplantation Exposure of Mouse Embryos to Palmitic Acid Results in Fetal Growth Restriction Followed by Catch-Up Growth in the Offspring1

Free fatty acids (FFAs) are energy substrates for many cell types, but in excess, some FFAs can accumulate in nonadipose cells, inducing apoptosis. Also known as lipotoxicity, this phenomenon may play a role in the development of obesity-related disease. Obesity is common among reproductive age wome...

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Veröffentlicht in:	Biology of reproduction 2011-10, Vol.85 (4), p.678-683
Hauptverfasser:	Jungheim, Emily S, Louden, Erica D, Chi, Maggie M.-Y, Frolova, Antonina I, Riley, Joan K, Moley, Kelle H
Format:	Artikel
Sprache:	eng
Schlagworte:	developmental biology developmental origins of health and disease early development embryo embryo culture metabolism
Online-Zugang:	Volltext
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