Effect of Leptin on Mouse Trophoblast Giant Cells1

Leptin plays a role in both energy homeostasis and reproduction, and it is required in early pregnancy. It stimulates metalloproteinase activity in cultured human trophoblasts and invasiveness of cultured mouse trophoblasts. Our goal has been to examine mechanisms that underpin the ability of leptin...

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Veröffentlicht in:	Biology of reproduction 2009-03, Vol.80 (3), p.415-424
Hauptverfasser:	Schulz, L. C, Widmaier, E. P, Qiu, J, Roberts, R. M
Format:	Artikel
Sprache:	eng
Schlagworte:	leptin matrix metalloproteinase MEK placenta signal transduction SOCS3 STAT3 trophoblast
Online-Zugang:	Volltext
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