Impaired Progesterone Production in Nr5a2+/− Mice Leads to a Reduction in Female Reproductive Function1

NR5A2 is an orphan nuclear receptor involved in cholesterol metabolism and embryogenesis. The high level of expression of NR5A2 in the ovary and its involvement in the regulation of steroidogenic gene expression also suggest a role for this transcription factor in female reproductive function. In vi...

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Veröffentlicht in:Biology of reproduction 2007-08, Vol.77 (2), p.217-225
Hauptverfasser: Labelle-Dumais, Cassandre, Paré, Jean-François, Bélanger, Luc, Farookhi, Riaz, Dufort, Daniel
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Sprache:eng
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