Effect of Cell Confluence on Production of Cloned Mice Using an Inbred Embryonic Stem Cell Line1

Mice have been successfully cloned from both somatic cells and hybrid embryonic stem (ES) cells. Heterozygosity of the donor ES cell genome has been suggested as a crucial factor for long-term survival of cloned mice. In the present study, an inbred ES cell line, HM-1 (129/Ola), and a well-tested ES...

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Veröffentlicht in:Biology of reproduction 2003-02, Vol.68 (2), p.595-603
Hauptverfasser: Gao, Shaorong, McGarry, Michelle, Ferrier, Tricia, Pallante, Benedetta, Gasparrini, Bianca, Fletcher, Judy, Harkness, Linda, De Sousa, Paul, McWhir, Jim, Wilmut, Ian
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Sprache:eng
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