Neonatal Exposure to Genistein Induces Estrogen Receptor (ER)α Expression and Multioocyte Follicles in the Maturing Mouse Ovary: Evidence for ERβ-Mediated and Nonestrogenic Actions

Outbred CD-1 mice were treated neonatally on Days 1–5 with the phytoestrogen, genistein (1, 10, or 100 μg per pup per day), and ovaries were collected on Days 5, 12, and 19. Ribonuclease protection assay analysis of ovarian mRNA showed that estrogen receptor β (ERβ) predominated over ERα in controls...

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Veröffentlicht in:	Biology of reproduction 2002-10, Vol.67 (4), p.1285-1296
Hauptverfasser:	Jefferson, Wendy N, Couse, John F, Padilla-Banks, Elizabeth, Korach, Kenneth S, Newbold, Retha R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Contents follicular development Fundamental and applied biological sciences. Psychology granulosa cells Mammalian female genital system mechanisms of hormone action Morphology. Physiology oocyte development steroid hormone receptors Vertebrates: reproduction
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