Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures

Abstract Assessment of neuroactive effects of chemicals in cell-based assays remains challenging as complex functional tissue is required for biologically relevant readouts. Recent in vitro models using rodent primary neural cultures grown on multielectrode arrays allow quantitative measurements of...

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Veröffentlicht in:	Toxicological sciences 2021-04, Vol.180 (2), p.295-312
Hauptverfasser:	Saavedra, Lorena, Wallace, Kathleen, Freudenrich, Theresa F, Mall, Moritz, Mundy, William R, Davila, Jorge, Shafer, Timothy J, Wernig, Marius, Haag, Daniel
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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