Field deployable technique for 90Sr emergency bioassay

Rapid bioassay is very important for immediate and near-term consequence management, which includes identifying contaminated individuals and providing necessary medical intervention during a radiological or nuclear emergency. This paper reports the application of a newly developed bioassay technique...

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Veröffentlicht in:Radiation protection dosimetry 2009-09, Vol.136 (2), p.82-86
Hauptverfasser: Li, C., Sadi, B. B., Moodie, G., Daka, J. N., Lai, E. P. C., Kramer, G. H.
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container_end_page 86
container_issue 2
container_start_page 82
container_title Radiation protection dosimetry
container_volume 136
creator Li, C.
Sadi, B. B.
Moodie, G.
Daka, J. N.
Lai, E. P. C.
Kramer, G. H.
description Rapid bioassay is very important for immediate and near-term consequence management, which includes identifying contaminated individuals and providing necessary medical intervention during a radiological or nuclear emergency. This paper reports the application of a newly developed bioassay technique for 90Sr in urine on a field deployable instrument, the Triathler®. Performance of this field technique for sensitivity, accuracy and repeatability is evaluated against bioassay criteria (ANSI N13.30). This field technique offers the following analytical merits: (1) minimum detectable activity of 121 Bq l−1 when 20 ml of urine is used; (2) relative bias of 11.1 % and relative precision of 3.2 % at the level of 45 Bq per 20 ml of urine and (3) sample turnaround time of less than 1 h. The technique meets the requirements for emergency bioassay when a committed effective dose of 0.5 Sv is used as the action dose threshold for medical intervention. Sample throughput can be significantly improved if this technique is automated.
doi_str_mv 10.1093/rpd/ncp153
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subjects Adult
Biological Assay
Humans
Radiation Monitoring - methods
Sensitivity and Specificity
Strontium Radioisotopes - analysis
Urinalysis - methods
Urine - chemistry
title Field deployable technique for 90Sr emergency bioassay
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