Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus

Objective. IL-33 has recently been found to be the specific ligand of ST2, an IL-1 receptor family member that is selectively expressed in Th2 cells and mediates Th2 response. This study aims to measure the serum levels of soluble ST2 (sST2) and IL-33 in patients with SLE and to examine their associ...

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2010-03, Vol.49 (3), p.520-527
Hauptverfasser:	Mok, Mo Yin, Huang, Fang Ping, Ip, Wai Ki, Lo, Yi, Wong, Fung Yi, Chan, Eric Yuk Tat, Lam, Kwok Fai, Xu, Damo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Antinuclear - blood Biological and medical sciences Biomarkers - blood Diseases of the osteoarticular system Dose-Response Relationship, Drug Epidemiologic Methods Female Glucocorticoids - administration & dosage Humans Immunosuppressive Agents - administration & dosage Interleukin-1 Receptor-Like 1 Protein Interleukin-33 Interleukins - blood Lupus Erythematosus, Systemic - drug therapy Lupus Erythematosus, Systemic - immunology Male Medical sciences Middle Aged Prednisolone - administration & dosage Receptors, Cell Surface - blood Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Soluble ST2 Systemic lupus erythematosus disease activity index T helper 2 immune response
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