Predictors of hepatotoxicity among patients treated with antituberculous medication

Hepatotoxicity in patients diagnosed with active tuberculosis (TB) is the commonest adverse effect of therapy. We sought to analyse trends in liver function in patients diagnosed with active TB and to determine predictors of hepatotoxicity. We studied 275 patients with active TB treated at the Mercy...

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Veröffentlicht in:	QJM : An International Journal of Medicine 2017-04, Vol.110 (4), p.219
Hauptverfasser:	Cusack, R P, Chawke, L, O'Brien, D J, O'Connor, B, O'Connor, T M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alanine Transaminase - blood Alkaline Phosphatase - blood Antitubercular Agents - adverse effects Antitubercular Agents - therapeutic use Aspartate Aminotransferases - blood Bilirubin - blood Chemical and Drug Induced Liver Injury - blood Chemical and Drug Induced Liver Injury - epidemiology Female gamma-Glutamyltransferase - blood Humans Incidence Ireland Liver - drug effects Liver Function Tests Male Middle Aged Predictive Value of Tests Retrospective Studies Risk Factors Tuberculosis - blood Tuberculosis - drug therapy
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