2395. An Interim Report of the Safety, Reactogenicity, and Immunogenicity of a Self-amplifying mRNA (samRNA) COVID-19 Vaccine GRT-R910 as a Booster in Healthy Adults

Abstract Background GRT-R910 (Gritstone bio, Inc), a self-amplifying mRNA (samRNA) vaccine expressing the spike protein plus T-cell epitopes of SARS-CoV-2 (D614G variant), was tested in a phase 1 study as a booster in healthy adults. Methods This phase 1 open-label, dose escalation study enrolled he...

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Veröffentlicht in:	Open forum infectious diseases 2023-11, Vol.10 (Supplement_2)
Hauptverfasser:	Whitaker, Jennifer, Rebolledo, Paulina, Rouphael, Nadine, Abate, Getahun, Babu, Tara M, Wald, Anna, Sahly, Hana El, Garbes, Pedro, Jooss, Karin, Allen, Andrew, McQuarrie, Lisa, Sitaula, Ranjan, Roberts, Paul C, Makhene, Mamodikoe, Posavad, Christine M, Juliana McElrath, M, De Rosa, Stephen, Coler, Rhea, Montefiori, David, Eaton, Amanda, Koelle, David M, Hoft, Daniel F
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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