EXTH-59. ESTABLISHING GAUSSIA LUCIFERASE REPORTER AS A BIOMARKER FOR ESTIMATING THERAPEUTIC RESPONSE AND PROGRESSION-FREE SURVIVAL IN PATIENT-DERIVED XENOGRAFT MODELS OF GLIOBLASTOMA

Abstract Serial monitoring of tumor burden in patient-derived xenograft (PDX) models used for testing new cancer drugs via MRI and other imaging techniques can be costly. We theorized that transducing the Gaussia luciferase (GLuc) reporter gene into glioma PDX models (GliomaPDOX) allows for GLuc to...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2024-11, Vol.26 (Supplement_8), p.viii250-viii250
Hauptverfasser:	McKinney, K’Ashé, Tse, Christopher, Wang, Chencai, Sanvito, Francesco, Nathanson, David, Ellingson, Benjamin M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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