PATH-13. MOLECULAR AND BIOLOGY CORRELATIVE RESULTS FROM THE PHASE 1B TRIAL OF UNESBULIN (PTC596) WITH RADIOTHERAPY IN CHILDREN NEWLY-DIAGNOSED WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND HIGH-GRADE GLIOMA (HGG): A REPORT FROM THE COLLABORATIVE NETWORK FOR NEURO-ONCOLOGY CLINICAL TRIALS (CONNECT)

Abstract BACKGROUND Within the CONNECT1702 trial of unesbulin (tubulin-binding agent causing BMI-1 modulation) with radiotherapy in patients with DIPG/HGG, tumor tissue was analyzed at diagnosis and/or autopsy for biology correlatives, enabling comprehensive, longitudinal molecular characterization....

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2024-11, Vol.26 (Supplement_8), p.viii180-viii180
Hauptverfasser:	Lazow, Margot, Baxter, Patricia, Kumar, Shiva Senthil, Mohamad, Maya, Mackay, Alan, Stanek, Joseph, Rodriguez, Diana, Palmer, Joshua, Leach, James, Mikael, Leonie, Thomas, Diana, Fuller, Christine, Boué, Daniel, Pierson, Christopher, Breneman, John, Li, Xiao-Nan, Salloum, Ralph, Ashley, David, de Blank, Peter, Hwang, Eugene, Leary, Sarah, Plant, Ashley, Fisher, Michael, Chi, Susan, Murala, Mythili, Weetall, Marla, Rance, Mark, Baird, John, D’Silva, Dhiren, O’Keefe, Kylie, Leonard, Jeffrey, Stewart, Clinton, Jones, Chris, Mardis, Elaine, Fouladi, Maryam, Drissi, Rachid
Format:	Artikel
Sprache:	eng
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