DDEL-15. PHARMACOKINETIC ANALYSIS OF CARBOPLATIN AND FLUORESCEIN BRAIN PENETRATION AND PERMANENCE FOLLOWING ULTRASOUND-BASED BLOOD-BRAIN BARRIER OPENING ON GLIOBLASTOMA CLINICAL TRIAL

Abstract The blood-brain barrier (BBB) impedes the passage of most circulating drugs into the brain. Low-intensity pulsed ultrasound with microbubbles (LIPU/MB) transiently opens the BBB, improving drug delivery to the brain. The implication of this transient BBB opening on parenchymal drug permanen...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2024-11, Vol.26 (Supplement_8), p.viii124-viii124
Hauptverfasser:	Habashy, Karl J, Synold, Tim, Feng, Ye, Kim, Kwang-Soo, Gomez, Cristal, Amidei, Christina, Ward, Rachel, VanderMolen, Sarah, Zarrieneh, Ashkan, Arrieta, Victor A, Fares, Jawad, Burdett, Kirsten B, Zhang, Hui, Dmello, Crismita, Chen, Li, Bebawy, John F, Canney, Michael, Stupp, Roger, Portnow, Jana, Sonabend, Adam M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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