KS05.6.A T-CELL THERAPY COMBINED WITH LOW-INTENSITY PULSED FOCUSED ULTRASOUND, MICROBUBBLES AND POLY-ICLC PROMOTES THE PRESENTATION OF BRAIN-DERIVED ANTIGENS, BREAKING CNS TOLERANCE AND INDUCING ACTIVE T-CELL RESPONSES

Abstract BACKGROUND Immunotherapies targeting glioma, such as chimeric antigen receptor (CAR) T cell therapies, offer new therapeutic opportunities; however, their application has yielded limited success. Due to the antigenic heterogeneity of gliomas, targeting a few or several antigens may still re...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2024-10, Vol.26 (Supplement_5), p.v7-v8
Hauptverfasser:	Gallus, M, Yamamichi, A, Andres Arrieta, V, Saijo, A, Chuntova, P, Haegelin, J, Phyu, S, Phung, L, Long, J, Lakshmanachetty, S, Nejo, T, Okada, K, Chen, L, Habashy, K, Gould, A, Amidei, C, Chang, C, Stupp, R, Canney, M, Sonabend, A, Okada, H
Format:	Artikel
Sprache:	eng
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