966 Targeting cAMP in ADPKD by small molecule activation of long form PDE4 enzymes

Abstract Background and Aims Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disorder, affecting over 12 million people worldwide. ADPKD is characterized by the uncontrolled growth of fluid-filled cysts in the kidney that can lead to kidney enlargement, loss...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2024-05, Vol.39 (Supplement_1)
Hauptverfasser:	Rowley, Adele, Henderson, David, Adam, Julia, Wang, Xiaofang, LI, Jiang, Irfan, Jaazba, Whitworth, Claire, Omar, Faisa, Kelleher, Catherine, Torres, Vicente
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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