MO207: A Phase 1/2, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BION-1301 in Healthy Volunteers and Adults with IGA Nephropathy

Abstract BACKGROUND AND AIMS Immunoglobulin A nephropathy (IgAN) is the leading cause of primary glomerulonephritis worldwide with limited treatment options, especially for high-risk patients [1]. BION-1301 is a novel humanized monoclonal antibody that blocks a proliferation-inducing ligand (APRIL),...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2022-05, Vol.37 (Supplement_3)
Hauptverfasser:	Barratt, Jonathan, Schwartz, Brian, Sorensen, Bess, Macdonald, Margaret, Tolentino, Jerlyn, Lo, Jeannette, King, Andrew, Prasad N Iyer, Sai, Glicklich, Alan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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