P0018GLOMERULAR ENDOTHELIAL CELL SENESCENCE DRIVES AGE-RELATED KIDNEY DISEASE THROUGH PAI-1

Abstract Background and Aims In age-related chronic kidney disease (CKD), the most frequent histological lesion observed is glomerulosclerosis. The molecular mechanisms involved in this deterioration process are unclear, but cellular senescence might play a role. Method By combining several murine m...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 2020-06, Vol.35 (Supplement_3)
Hauptverfasser: Cohen, Camille, Oceanc, Legoff, Soysouvanh, Frederic, Tanou, Marine, Vasseur, Florence, Nguyen, Clement, Amrouche, Lucile, Meunier, Tanguy, Rabant, Marion, Nochy, Dominique, Legendre, Christophe, Anglicheau, Dany, Milliat, Fabien, Terzi, Fabiola
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Sprache:eng
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