Comparison of the activities of bacterial and mammalian nucleotide excision repair systems for DNA-protein crosslinks

Abstract Endogenous and environmental genotoxic agents produce DNA damage and induce cell death and mutations. The repair mechanisms of base lesions and single and double strand breaks have been well characterized in both prokaryotic and eukaryotic cells. However, the molecular pathways that repair...

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Veröffentlicht in:	Nucleic Acids Symposium Series 2009, Vol.53 (1), p.225-226
Hauptverfasser:	Nakano, Toshiaki, Salem, Amir M.H., Terato, Hiroaki, Pack, Seung Pil, Makino, Keisuke, Ide, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA - chemistry DNA Damage DNA Repair Endodeoxyribonucleases - metabolism Escherichia coli Proteins - metabolism HeLa Cells Humans Proteins - chemistry
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