Pyrrolidine analogues of nucleosides and nucleotides
Abstract Among the structurally diverse nucleoside phosphonic acids, several compounds possessing strong antiviral properties have been found. Our effort in this area was focused to the synthesis of novel compounds - pyrrolidine-based nucleoside phosphonic acids and their derivatives.
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Veröffentlicht in: | Nucleic Acids Symposium Series 2008, Vol.52 (1), p.577-578 |
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container_title | Nucleic Acids Symposium Series |
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creator | Rejman, Dominik Pohl, Radek Kovačková, Soňa Kočalka, Petr Švenková, Alžběta Šanderová, Hana Krásný, Libor Rosenberg, Ivan |
description | Abstract
Among the structurally diverse nucleoside phosphonic acids, several compounds possessing strong antiviral properties have been found. Our effort in this area was focused to the synthesis of novel compounds - pyrrolidine-based nucleoside phosphonic acids and their derivatives. |
doi_str_mv | 10.1093/nass/nrn292 |
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Among the structurally diverse nucleoside phosphonic acids, several compounds possessing strong antiviral properties have been found. Our effort in this area was focused to the synthesis of novel compounds - pyrrolidine-based nucleoside phosphonic acids and their derivatives.</description><subject>Antiviral Agents - chemical synthesis</subject><subject>Antiviral Agents - chemistry</subject><subject>Nucleosides - chemical synthesis</subject><subject>Nucleosides - chemistry</subject><subject>Nucleotides - chemical synthesis</subject><subject>Nucleotides - chemistry</subject><subject>Organophosphonates - chemistry</subject><subject>Pyrrolidines - chemistry</subject><issn>0261-3166</issn><issn>1746-8272</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMottSevEtPepC1-dpkc5RSP6CgBz2HbDKRlW1Sk-6h_95ddsGbM4fhhYeX4UHomuAHghVbB5PzOqRAFT1DcyK5KCoq6TmaYypIwYgQM7TM-Rv3wzGWSl6iGamkFCUhc8TfTynFtnFNgJUJpo1fHeRV9KvQ2RZiblwfTXBTPg75Cl1402ZYTneBPp-2H5uXYvf2_Lp53BWWKHosSlpXpQJQHBwlJevX0popppSh1rmy8pRwb72voC69xFYAASUsF7ymjLMFuht7Dyn-9G8d9b7JFtrWBIhd1pIxyangA3k_kjbFnBN4fUjN3qSTJlgPovQgSo-ievpm6u3qPbg_dtLSA7cjELvDv02_4rtx2Q</recordid><startdate>2008</startdate><enddate>2008</enddate><creator>Rejman, Dominik</creator><creator>Pohl, Radek</creator><creator>Kovačková, Soňa</creator><creator>Kočalka, Petr</creator><creator>Švenková, Alžběta</creator><creator>Šanderová, Hana</creator><creator>Krásný, Libor</creator><creator>Rosenberg, Ivan</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2008</creationdate><title>Pyrrolidine analogues of nucleosides and nucleotides</title><author>Rejman, Dominik ; Pohl, Radek ; Kovačková, Soňa ; Kočalka, Petr ; Švenková, Alžběta ; Šanderová, Hana ; Krásný, Libor ; Rosenberg, Ivan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c192t-52b859ee94ed2153535c2b39399a2cdd58f214fcff8eb5f70c6e1e96c464b2343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Antiviral Agents - chemical synthesis</topic><topic>Antiviral Agents - chemistry</topic><topic>Nucleosides - chemical synthesis</topic><topic>Nucleosides - chemistry</topic><topic>Nucleotides - chemical synthesis</topic><topic>Nucleotides - chemistry</topic><topic>Organophosphonates - chemistry</topic><topic>Pyrrolidines - chemistry</topic><toplevel>online_resources</toplevel><creatorcontrib>Rejman, Dominik</creatorcontrib><creatorcontrib>Pohl, Radek</creatorcontrib><creatorcontrib>Kovačková, Soňa</creatorcontrib><creatorcontrib>Kočalka, Petr</creatorcontrib><creatorcontrib>Švenková, Alžběta</creatorcontrib><creatorcontrib>Šanderová, Hana</creatorcontrib><creatorcontrib>Krásný, Libor</creatorcontrib><creatorcontrib>Rosenberg, Ivan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nucleic Acids Symposium Series</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Rejman, Dominik</au><au>Pohl, Radek</au><au>Kovačková, Soňa</au><au>Kočalka, Petr</au><au>Švenková, Alžběta</au><au>Šanderová, Hana</au><au>Krásný, Libor</au><au>Rosenberg, Ivan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pyrrolidine analogues of nucleosides and nucleotides</atitle><jtitle>Nucleic Acids Symposium Series</jtitle><addtitle>Nucleic Acids Symp Ser (Oxf)</addtitle><date>2008</date><risdate>2008</risdate><volume>52</volume><issue>1</issue><spage>577</spage><epage>578</epage><pages>577-578</pages><issn>0261-3166</issn><eissn>1746-8272</eissn><abstract>Abstract
Among the structurally diverse nucleoside phosphonic acids, several compounds possessing strong antiviral properties have been found. Our effort in this area was focused to the synthesis of novel compounds - pyrrolidine-based nucleoside phosphonic acids and their derivatives.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>18776511</pmid><doi>10.1093/nass/nrn292</doi><tpages>2</tpages></addata></record> |
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subjects | Antiviral Agents - chemical synthesis Antiviral Agents - chemistry Nucleosides - chemical synthesis Nucleosides - chemistry Nucleotides - chemical synthesis Nucleotides - chemistry Organophosphonates - chemistry Pyrrolidines - chemistry |
title | Pyrrolidine analogues of nucleosides and nucleotides |
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