In vitro evolution of flexizymes that function under the conditions in translation system

Flexizyme is an artificial ribozyme capable of acylating any kinds of tRNAs with virtually no limitation of acid donor substrates. Although the flexizyme system is a highly flexible tRNA acylation tool, it requires relatively high Mg2+ concentrations (>50 mM) for the full function. For instance,...

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Veröffentlicht in:	Nucleic Acids Symposium Series 2006-11, Vol.50 (1), p.299-300
Hauptverfasser:	Ohuchi, Masaki, Murakami, Hiroshi, Suga, Hiroaki
Format:	Artikel
Sprache:	eng
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