Recognition of DNA with assembly of minor groove binders mediated by metal complexation

Genome-targeting molecules would have broad application as probes in genomic study. We recently developed the ligands (Bpy-H) connecting the Hoechst33258 skeleton for DNA binding and 2,2′-bipyridine for Cu2+ complexation. It was shown that L-Bpy-H with a long linker exhibited Cu2+-mediated assembly...

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Veröffentlicht in:	Nucleic Acids Symposium Series 2006-11, Vol.50 (1), p.161-162
Hauptverfasser:	Kataoka, Tomonobu, Tanada, Mikimasa, Onishi, Ippei, Sasaki, Shigeki
Format:	Artikel
Sprache:	eng
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