Comparing the pharmacokinetics of 13α,21-dihydroeurycomanone and eurycomanone exclusively enriched in Eurycoma longifolia extracts and their spermatogenesis enhancement in andrographolide-induced oligospermia in rats

Abstract Objectives The quassinoids eurycomanone (EN) and 13α,21-dihydroeurycomanone (DHY) of Eurycoma longifolia Jack are reported to enhance spermatogenesis. This study aims to profile the pharmacokinetics of DHY, a minor and hitherto unstudied constituent, evaluate its spermatogenesis enhancement...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2021-03, Vol.73 (2), p.161-168
Hauptverfasser:	Chung, Wan-Jie, Chan, Kit-Lam, Lee, Chong-Yew
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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