Toxicity of Extended Adjuvant Therapy With Aromatase Inhibitors in Early Breast Cancer: A Systematic Review and Meta-analysis

A number of randomized controlled trials (RCTs) have reported improvement in breast cancer outcomes from extending treatment with aromatase inhibitors (AIs) beyond the initial five years after diagnosis. However, the toxicity profile of extended AIs is uncertain. We identified RCTs that compared ext...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2018-01, Vol.110 (1), p.31-39
Hauptverfasser:	Goldvaser, Hadar, Barnes, Tristan A, Šeruga, Boštjan, Cescon, David W, Ocaña, Alberto, Ribnikar, Domen, Amir, Eitan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatase Inhibitors - administration & dosage Aromatase Inhibitors - adverse effects Breast Neoplasms - drug therapy Breast Neoplasms - surgery Cardiovascular Diseases - epidemiology Chemotherapy, Adjuvant - adverse effects Chemotherapy, Adjuvant - methods Female Fractures, Bone - epidemiology Humans Mortality Neoplasms, Second Primary - epidemiology Randomized Controlled Trials as Topic Time Factors Withholding Treatment
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!