Interferon-gamma induces epithelial reprogramming driving CXCL11-mediated T-cell migration

The cytokine interferon-gamma plays a multifaceted role in intestinal immune responses ranging from anti- to proinflammatory depending on the setting. Here, using a 3D co-culture system based on human intestinal epithelial organoids, we explore the capacity of interferon-gamma exposure to reprogram...

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Veröffentlicht in:Journal of leukocyte biology 2024-10
Hauptverfasser: Cutilli, Alessandro, Jansen, Suze A, Paolucci, Francesca, van Hoesel, Marliek, Frederiks, Cynthia L, Mulder, Tessa A M, Chalkiadakis, Theofilos, Mokry, Michal, Prekovic, Stefan, Mocholi, Enric, Lindemans, Caroline A, Coffer, Paul J
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Sprache:eng
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