Evaluation of combinations of putative anti-biofilm agents and antibiotics to eradicate biofilms of Staphylococcus aureus and Pseudomonas aeruginosa

To evaluate potential anti-biofilm agents for their ability to enhance the activity of antibiotics for local treatment of localized biofilm infections. Staphylococcus aureus and Pseudomonas aeruginosa in vitro biofilm models were developed. The putative antibiotic enhancers N-acetylcysteine, acetyls...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2017-09, Vol.72 (9), p.2531-2538
Hauptverfasser:	Belfield, Katherine, Bayston, Roger, Hajduk, Nadzieja, Levell, Georgia, Birchall, John P, Daniel, Matija
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Biofilms - drug effects Ciprofloxacin - pharmacology Clindamycin - pharmacology Deoxyribonuclease I - pharmacology Gentamicins - pharmacology Humans Hydrogen Peroxide - pharmacology Microbial Sensitivity Tests Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - physiology Soaps - chemistry Soaps - pharmacology Staphylococcus aureus - drug effects Staphylococcus aureus - physiology Vancomycin - pharmacology
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