Nephrotoxicity of continuous amphotericin B in critically ill patients with abdominal sepsis: a retrospective analysis with propensity score matching

Continuous infusion of conventional amphotericin B (CCAB) is used in ICUs for pre-emptive treatment of invasive fungal infections. Amphotericin B has previously been associated with nephrotoxicity. To investigate if CCAB with therapeutic drug monitoring (TDM) results in renal impairment over time in...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2021-12, Vol.77 (1), p.246-252
Hauptverfasser:	Geersing, T H, Franssen, E J F, Spronk, P E, van Kan, H J M, den Reijer, M, van der Voort, P H J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B - adverse effects Critical Illness - therapy Humans Propensity Score Renal Insufficiency Retrospective Studies Sepsis - drug therapy Sepsis - microbiology
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