In the presence of IL-21 human cord blood T cells differentiate to IL-10-producing T h 1 but not T h 17 or T h 2 cells

IL-21, a member of the IL-2 cytokine family, is mainly produced by activated CD4+ T cells and controls the activity of immune and also non-immune cells. As a pleiotropic cytokine, IL-21 acts on both innate and adaptive immune responses, suggesting that IL-21 may be a master regulator of the T-cell-d...

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Veröffentlicht in:	International immunology 2013-03, Vol.25 (3), p.157-169
Hauptverfasser:	Doganci, Aysefa, Birkholz, Julia, Gehring, Stephan, Puhl, Alexander G., Zepp, Fred, Meyer, Claudius U.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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