Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice

Abstract BACKGROUND Infertility is a major issue in human reproductive health, affecting an estimated 15% of couples worldwide. Infertility can result from disorders of sex development (DSD) or from reproductive endocrine disorders (REDs) with onset in infancy, early childhood or adolescence. Male i...

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Veröffentlicht in:	Human reproduction update 2021-01, Vol.27 (1), p.154-189
Hauptverfasser:	Jiao, Shi-Ya, Yang, Yi-Hong, Chen, Su-Ren
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Humans Infertility, Female - genetics Infertility, Male - genetics Loss of Function Mutation Male Mice Mice, Knockout Sperm Motility Spermatozoa
Online-Zugang:	Volltext
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