The ‘incessant menstruation’ hypothesis: a mechanistic ovarian cancer model with implications for prevention

Serous, endometrioid, clear cell and mucinous histotypes are the most common epithelial ovarian cancer. Most serous cancers appear to originate from precursor lesions at the fimbriated tubal end, whereas most endometrioid and clear cell cancers seem to derive from atypical endometriosis. Data regard...

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Veröffentlicht in:	Human reproduction (Oxford) 2011-09, Vol.26 (9), p.2262-2273
Hauptverfasser:	Vercellini, Paolo, Crosignani, Piergiorgio, Somigliana, Edgardo, Viganò, Paola, Buggio, Laura, Bolis, Giorgio, Fedele, Luigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Contraceptives, Oral - therapeutic use Endometriosis - complications Female Gynecology. Andrology. Obstetrics Humans Iron - metabolism Medical sciences Menstruation Disturbances - complications Ovarian Neoplasms - complications Ovarian Neoplasms - etiology Ovarian Neoplasms - prevention & control Oxidative Stress Salpingectomy
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