P154 HUMAN CORONARY INFLAMMATION AT CORONARY COMPUTED TOMOGRAPHY IN PATIENTS WITH INOCA

Abstract Background A new imaging metric using coronary computed tomography angiography (CCTA), addressing the peri–coronary adipose tissue (PCAT) computed tomography (CT) attenuation, has been clinically validated. This method provides information regarding coronary inflammation. It is unclear how coronary inflammation affects microvascular function. The non–invasive evaluation of coronary flowvelocity reserve is widely used in clinical practice using Doppler measurement on the left anterior descending coronary artery (CFVR–lad) during stress–echocardiography (SE).We hypothesize that coronary inflammation affects CFVR–lad and, in the absence of overt CAD, they are significantly correlated. Methods We evaluated the relationship between coronary inflammation (by PCAT CT attenuation) and coronary microvascular function (by CFVR–lad) in subjects with no or non–obstructive (diameter stenosis