C57 ASSOCIATION OF CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY AND STRESS–ECHOCARDIOGRAPHY WITH LONG–TERM CARDIAC OUTCOME: A COMPARISON STUDY

C57 ASSOCIATION OF CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY AND STRESS–ECHOCARDIOGRAPHY WITH LONG–TERM CARDIAC OUTCOME: A COMPARISON STUDY

Abstract Aims The study aims to assess which variables on coronary computed tomography angiography (CTA) and vasodilator stress–echocardiography (SE) are best associated with long–term cardiac outcome in patients presenting for suspected chronic coronary syndrome (CCS) who performed both tests. Meth...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:European heart journal supplements 2023-05, Vol.25 (Supplement_D), p.D24-D24
Hauptverfasser: Tuttolomondo, D, Gaibazzi, N
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page D24
container_issue Supplement_D
container_start_page D24
container_title European heart journal supplements
container_volume 25
creator Tuttolomondo, D
Gaibazzi, N
description Abstract Aims The study aims to assess which variables on coronary computed tomography angiography (CTA) and vasodilator stress–echocardiography (SE) are best associated with long–term cardiac outcome in patients presenting for suspected chronic coronary syndrome (CCS) who performed both tests. Methods We identified 397 patients with suspected CCS who, between 2007 and 2019, underwent both SE and CTA within 30 days. Coronary artery calcium score (CACS) and the number of coronary arteries with diameter stenosis >50% were assessed on CTA. The presence of reversible regional wall motion abnormalities (RWMA) and reduced Doppler coronary flow velocity reserve in the left anterior descending coronary artery (CFVR) were assessed on SE. The association of SE and CTA variables with cardiac outcome (cardiac death or myocardial infarction) was assessed using Fine and Gray competing risk models. Results During a median follow–up of 10 years, 38 (9.6%) patients experienced a non–fatal myocardial infarction and 19 (4.8%) died from a cardiac cause. RWMA (HR 7.189, p
doi_str_mv 10.1093/eurheartjsupp/suad111.056
format Article
fullrecord <record><control><sourceid>oup_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1093_eurheartjsupp_suad111_056</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/eurheartjsupp/suad111.056</oup_id><sourcerecordid>10.1093/eurheartjsupp/suad111.056</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1466-64322fdc13e89c1f9c312417451947b8e6a4d3766089f5b912a581223398a3e33</originalsourceid><addsrcrecordid>eNqVkM1Og0AAhDdGE2v1HdYHoN1_wNtmoUDSsg0s0Z4IpRBtNCUgB28-gRff0CeR_kTj0dNMMpmZ5APgFqMJRi6dVn37WBXt67brm2ba9cUGYzxBXJyBEeacWcTB_HzvCbJswR8uwVXXbREi1GFoBD4Ut6FMU60iaSIdQz2DSic6lslqMItlZnwPGr3QQSKX4QrKOIh-vQdTk_hp-vX-6atQK5l4P-l9ZEI413EwhMZPFvCQSgV1ZoZl_w7Kw4NMonQ4Tk3mra7BRV08d9XNSccgm_lGhdZcB5GSc6vETAhLMEpIvSkxrRy3xLVbUkwYthnHLrPXTiUKtqG2EMhxa752MSm4gwmh1HUKWlE6Bu5xt2x3XddWdd60Ty9F-5ZjlO_B5n_A5iew-QB26LJjd9c3_6h9A0D5e4s</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>C57 ASSOCIATION OF CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY AND STRESS–ECHOCARDIOGRAPHY WITH LONG–TERM CARDIAC OUTCOME: A COMPARISON STUDY</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Tuttolomondo, D ; Gaibazzi, N</creator><creatorcontrib>Tuttolomondo, D ; Gaibazzi, N</creatorcontrib><description>Abstract Aims The study aims to assess which variables on coronary computed tomography angiography (CTA) and vasodilator stress–echocardiography (SE) are best associated with long–term cardiac outcome in patients presenting for suspected chronic coronary syndrome (CCS) who performed both tests. Methods We identified 397 patients with suspected CCS who, between 2007 and 2019, underwent both SE and CTA within 30 days. Coronary artery calcium score (CACS) and the number of coronary arteries with diameter stenosis &gt;50% were assessed on CTA. The presence of reversible regional wall motion abnormalities (RWMA) and reduced Doppler coronary flow velocity reserve in the left anterior descending coronary artery (CFVR) were assessed on SE. The association of SE and CTA variables with cardiac outcome (cardiac death or myocardial infarction) was assessed using Fine and Gray competing risk models. Results During a median follow–up of 10 years, 38 (9.6%) patients experienced a non–fatal myocardial infarction and 19 (4.8%) died from a cardiac cause. RWMA (HR 7.189, p&lt;0.001) and a lower CFVR (HR 0.034, p&lt;0.001) on SE, CACS (HR 1.004, p&lt;0.001) and the number of &gt;50% stenosed coronary vessels (HR 1.975, p&lt;0.001) on CTA were each associated with cardiac events. After adjusting for covariates, only CACS and CFVR remained associated (both p&lt;0.001) with cardiac outcome. Conclusion Our data suggest that only CFVR on SE and CACS on CTA are independently and strongly associated with long–term cardiac outcome, unlike RWMA or the number of stenosed coronary arteries, usually considered the hallmarks of coronary artery disease on each test.</description><identifier>ISSN: 1520-765X</identifier><identifier>EISSN: 1554-2815</identifier><identifier>DOI: 10.1093/eurheartjsupp/suad111.056</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><ispartof>European heart journal supplements, 2023-05, Vol.25 (Supplement_D), p.D24-D24</ispartof><rights>The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Tuttolomondo, D</creatorcontrib><creatorcontrib>Gaibazzi, N</creatorcontrib><title>C57 ASSOCIATION OF CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY AND STRESS–ECHOCARDIOGRAPHY WITH LONG–TERM CARDIAC OUTCOME: A COMPARISON STUDY</title><title>European heart journal supplements</title><description>Abstract Aims The study aims to assess which variables on coronary computed tomography angiography (CTA) and vasodilator stress–echocardiography (SE) are best associated with long–term cardiac outcome in patients presenting for suspected chronic coronary syndrome (CCS) who performed both tests. Methods We identified 397 patients with suspected CCS who, between 2007 and 2019, underwent both SE and CTA within 30 days. Coronary artery calcium score (CACS) and the number of coronary arteries with diameter stenosis &gt;50% were assessed on CTA. The presence of reversible regional wall motion abnormalities (RWMA) and reduced Doppler coronary flow velocity reserve in the left anterior descending coronary artery (CFVR) were assessed on SE. The association of SE and CTA variables with cardiac outcome (cardiac death or myocardial infarction) was assessed using Fine and Gray competing risk models. Results During a median follow–up of 10 years, 38 (9.6%) patients experienced a non–fatal myocardial infarction and 19 (4.8%) died from a cardiac cause. RWMA (HR 7.189, p&lt;0.001) and a lower CFVR (HR 0.034, p&lt;0.001) on SE, CACS (HR 1.004, p&lt;0.001) and the number of &gt;50% stenosed coronary vessels (HR 1.975, p&lt;0.001) on CTA were each associated with cardiac events. After adjusting for covariates, only CACS and CFVR remained associated (both p&lt;0.001) with cardiac outcome. Conclusion Our data suggest that only CFVR on SE and CACS on CTA are independently and strongly associated with long–term cardiac outcome, unlike RWMA or the number of stenosed coronary arteries, usually considered the hallmarks of coronary artery disease on each test.</description><issn>1520-765X</issn><issn>1554-2815</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqVkM1Og0AAhDdGE2v1HdYHoN1_wNtmoUDSsg0s0Z4IpRBtNCUgB28-gRff0CeR_kTj0dNMMpmZ5APgFqMJRi6dVn37WBXt67brm2ba9cUGYzxBXJyBEeacWcTB_HzvCbJswR8uwVXXbREi1GFoBD4Ut6FMU60iaSIdQz2DSic6lslqMItlZnwPGr3QQSKX4QrKOIh-vQdTk_hp-vX-6atQK5l4P-l9ZEI413EwhMZPFvCQSgV1ZoZl_w7Kw4NMonQ4Tk3mra7BRV08d9XNSccgm_lGhdZcB5GSc6vETAhLMEpIvSkxrRy3xLVbUkwYthnHLrPXTiUKtqG2EMhxa752MSm4gwmh1HUKWlE6Bu5xt2x3XddWdd60Ty9F-5ZjlO_B5n_A5iew-QB26LJjd9c3_6h9A0D5e4s</recordid><startdate>20230518</startdate><enddate>20230518</enddate><creator>Tuttolomondo, D</creator><creator>Gaibazzi, N</creator><general>Oxford University Press</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20230518</creationdate><title>C57 ASSOCIATION OF CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY AND STRESS–ECHOCARDIOGRAPHY WITH LONG–TERM CARDIAC OUTCOME: A COMPARISON STUDY</title><author>Tuttolomondo, D ; Gaibazzi, N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1466-64322fdc13e89c1f9c312417451947b8e6a4d3766089f5b912a581223398a3e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tuttolomondo, D</creatorcontrib><creatorcontrib>Gaibazzi, N</creatorcontrib><collection>CrossRef</collection><jtitle>European heart journal supplements</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tuttolomondo, D</au><au>Gaibazzi, N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>C57 ASSOCIATION OF CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY AND STRESS–ECHOCARDIOGRAPHY WITH LONG–TERM CARDIAC OUTCOME: A COMPARISON STUDY</atitle><jtitle>European heart journal supplements</jtitle><date>2023-05-18</date><risdate>2023</risdate><volume>25</volume><issue>Supplement_D</issue><spage>D24</spage><epage>D24</epage><pages>D24-D24</pages><issn>1520-765X</issn><eissn>1554-2815</eissn><abstract>Abstract Aims The study aims to assess which variables on coronary computed tomography angiography (CTA) and vasodilator stress–echocardiography (SE) are best associated with long–term cardiac outcome in patients presenting for suspected chronic coronary syndrome (CCS) who performed both tests. Methods We identified 397 patients with suspected CCS who, between 2007 and 2019, underwent both SE and CTA within 30 days. Coronary artery calcium score (CACS) and the number of coronary arteries with diameter stenosis &gt;50% were assessed on CTA. The presence of reversible regional wall motion abnormalities (RWMA) and reduced Doppler coronary flow velocity reserve in the left anterior descending coronary artery (CFVR) were assessed on SE. The association of SE and CTA variables with cardiac outcome (cardiac death or myocardial infarction) was assessed using Fine and Gray competing risk models. Results During a median follow–up of 10 years, 38 (9.6%) patients experienced a non–fatal myocardial infarction and 19 (4.8%) died from a cardiac cause. RWMA (HR 7.189, p&lt;0.001) and a lower CFVR (HR 0.034, p&lt;0.001) on SE, CACS (HR 1.004, p&lt;0.001) and the number of &gt;50% stenosed coronary vessels (HR 1.975, p&lt;0.001) on CTA were each associated with cardiac events. After adjusting for covariates, only CACS and CFVR remained associated (both p&lt;0.001) with cardiac outcome. Conclusion Our data suggest that only CFVR on SE and CACS on CTA are independently and strongly associated with long–term cardiac outcome, unlike RWMA or the number of stenosed coronary arteries, usually considered the hallmarks of coronary artery disease on each test.</abstract><cop>US</cop><pub>Oxford University Press</pub><doi>10.1093/eurheartjsupp/suad111.056</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1520-765X
ispartof European heart journal supplements, 2023-05, Vol.25 (Supplement_D), p.D24-D24
issn 1520-765X
1554-2815
language eng
recordid cdi_crossref_primary_10_1093_eurheartjsupp_suad111_056
source Oxford University Press Journals All Titles (1996-Current); Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
title C57 ASSOCIATION OF CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY AND STRESS–ECHOCARDIOGRAPHY WITH LONG–TERM CARDIAC OUTCOME: A COMPARISON STUDY
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-20T16%3A30%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-oup_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=C57%20ASSOCIATION%20OF%20CORONARY%20COMPUTED%20TOMOGRAPHY%20ANGIOGRAPHY%20AND%20STRESS%E2%80%93ECHOCARDIOGRAPHY%20WITH%20LONG%E2%80%93TERM%20CARDIAC%20OUTCOME:%20A%20COMPARISON%20STUDY&rft.jtitle=European%20heart%20journal%20supplements&rft.au=Tuttolomondo,%20D&rft.date=2023-05-18&rft.volume=25&rft.issue=Supplement_D&rft.spage=D24&rft.epage=D24&rft.pages=D24-D24&rft.issn=1520-765X&rft.eissn=1554-2815&rft_id=info:doi/10.1093/eurheartjsupp/suad111.056&rft_dat=%3Coup_cross%3E10.1093/eurheartjsupp/suad111.056%3C/oup_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_oup_id=10.1093/eurheartjsupp/suad111.056&rfr_iscdi=true