P1623Activation of invariant natural killer T cells by alpha-galactosylceramide ameliorates doxorubicin-induced cardiotoxicity in mice

Abstract Objective Doxorubicin (DOX) is an effective antineoplastic agent commonly used to treat many types of cancer but its clinical use is limited because of cardiotoxicity, which might proceed to irreversible cardiac dysfunction in a dose-dependent manner. The precise mechanism of DOX-induced ca...

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Veröffentlicht in:	European heart journal 2019-10, Vol.40 (Supplement_1)
Hauptverfasser:	Obata, Y, Ishimori, N, Saito, A, Kinugawa, S, Nakano, I, Kakutani, N, Yamanashi, K, Anzai, T
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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