Sarcomere disassembly and transfection efficiency in proliferating human iPSC-derived cardiomyocytes

Abstract Introduction Proper contraction of cardiomyocytes (CMs) is dictated by the architecture of the sarcomeres and appears together with polyploidy inversely correlated with limited self-renewal and regeneration of the adult heart. This limited regenerative potential correlates with the decrease...

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Veröffentlicht in:	European heart journal 2023-11, Vol.44 (Supplement_2)
Hauptverfasser:	Yuan, Q, Maas, R, Brouwer, E, Sluijter, J, Van Der Velden, J, Buikema, J A N W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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