P1601 Relationship between aortic distensibility and aortic regurgitation assessed by CMR in bicuspid valve patients
Abstract Funding Acknowledgements Spanish Ministry of Economy and Competitiveness RTC-2016-5152-1, ISCIII PI17/00381, La Marató de TV3 (20151330), Eur FP7/People 267128 and CIBERCV BACKGROUND The severity of aortic regurgitation can be evaluated with cardiac magnetic resonance (CMR) through calculat...
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| creator | La Mura, L Teixido-Tura, G Guala, A Ruiz-Munoz, A Lopez Sainz, A Valente, F Pisaniello, M Strada, S Granato, C Galian Gay, L Gonzalez-Alujas, T Servato, M L Ferreira, I Rodriguez-Palomares, J F Evangelista, A |
| description | Abstract
Funding Acknowledgements
Spanish Ministry of Economy and Competitiveness RTC-2016-5152-1, ISCIII PI17/00381, La Marató de TV3 (20151330), Eur FP7/People 267128 and CIBERCV
BACKGROUND
The severity of aortic regurgitation can be evaluated with cardiac magnetic resonance (CMR) through calculation of regurgitant fraction (RF) in phase contrast sequences acquired at the aortic root (as close as possible to the aortic valve). However, the impact of aortic distensibility in this evaluation remains unkown.
PURPOSE
The aim of the study was to evaluate the relation between aortic distensibility and RF valve in bicuspid aortic valve patients.
METHODS
We enrolled bicuspid aortic valve patients without significant aortic stenosis (maximum velocity |
| doi_str_mv | 10.1093/ehjci/jez319.1019 |
| format | Article |
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Funding Acknowledgements
Spanish Ministry of Economy and Competitiveness RTC-2016-5152-1, ISCIII PI17/00381, La Marató de TV3 (20151330), Eur FP7/People 267128 and CIBERCV
BACKGROUND
The severity of aortic regurgitation can be evaluated with cardiac magnetic resonance (CMR) through calculation of regurgitant fraction (RF) in phase contrast sequences acquired at the aortic root (as close as possible to the aortic valve). However, the impact of aortic distensibility in this evaluation remains unkown.
PURPOSE
The aim of the study was to evaluate the relation between aortic distensibility and RF valve in bicuspid aortic valve patients.
METHODS
We enrolled bicuspid aortic valve patients without significant aortic stenosis (maximum velocity <2.5 m/s) and connective tissue disease. All patients underwent a CMR study with phase contrast sequences for evaluation of regurgitant fraction at the level of the aortic valve. Aortic regurgitation was considered as mild, moderate or severe depending on RF value (mild <15%; moderate 15-30%; severe >30%). Furthermore we used cine-sequences of aortic root, ascending and proximal descending aorta to estimate aortic diameters and distensibilities, using Art Fun software. Distensibility was calculated as (change in aortic area between systole and diastole/diastolic area)/brachial pulse pressure.
RESULTS
A total of 98 bicuspid aortic valve patients were included (30% female, 49.7 ± 14.5 years). 75 (76,5%) AR was mild, 17 (17,4%) moderate and 6 (6,1%) severe. RF valvewas significantly correlated with aortic root diameter (r= 0.430 y p < 0.001 )and aortic distensibility at the level of the ascending (r = 0.273 p =0.016) and descending aorta (r = 0.502 and p< 0.001). Aortic distensibility was positively correlated with RFvalve even after adjustment for aortic diameter ( p = 0.002 and p <0.001 respectively) . (Table) (IMG)
CONCLUSIONS
In our study, aortic regurgitation in bicuspid valve patients, evaluated by CMR using RF valve, is related to aortic distensibility. Thus, aortic distensibility should be included in the evaluation of aortic regurgitation by CMR as additional parameter. However, longitudinal studies are needed to evaluate the impact of including aortic distensibility in the evaluation of AR severity by CMR.
AR SEVERITY
MILD
MODERATE
SEVERE
Descending aorta distensibility(mean ± std. deviation)
2693,68 ± 997,5
3285,8 ±1952,7
5042,99 ±2873,44
Correlation between AR severity (by RFvalve) and descending aorta distensibility
Abstract P1601 Figure.</description><identifier>ISSN: 2047-2404</identifier><identifier>EISSN: 2047-2412</identifier><identifier>DOI: 10.1093/ehjci/jez319.1019</identifier><language>eng</language><publisher>Oxford University Press</publisher><ispartof>European heart journal cardiovascular imaging, 2020-01, Vol.21 (Supplement_1)</ispartof><rights>Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2020. For permissions please email: Journals.permissions@oup.com. 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1584,27924,27925</link.rule.ids></links><search><creatorcontrib>La Mura, L</creatorcontrib><creatorcontrib>Teixido-Tura, G</creatorcontrib><creatorcontrib>Guala, A</creatorcontrib><creatorcontrib>Ruiz-Munoz, A</creatorcontrib><creatorcontrib>Lopez Sainz, A</creatorcontrib><creatorcontrib>Valente, F</creatorcontrib><creatorcontrib>Pisaniello, M</creatorcontrib><creatorcontrib>Strada, S</creatorcontrib><creatorcontrib>Granato, C</creatorcontrib><creatorcontrib>Galian Gay, L</creatorcontrib><creatorcontrib>Gonzalez-Alujas, T</creatorcontrib><creatorcontrib>Servato, M L</creatorcontrib><creatorcontrib>Ferreira, I</creatorcontrib><creatorcontrib>Rodriguez-Palomares, J F</creatorcontrib><creatorcontrib>Evangelista, A</creatorcontrib><title>P1601 Relationship between aortic distensibility and aortic regurgitation assessed by CMR in bicuspid valve patients</title><title>European heart journal cardiovascular imaging</title><description>Abstract
Funding Acknowledgements
Spanish Ministry of Economy and Competitiveness RTC-2016-5152-1, ISCIII PI17/00381, La Marató de TV3 (20151330), Eur FP7/People 267128 and CIBERCV
BACKGROUND
The severity of aortic regurgitation can be evaluated with cardiac magnetic resonance (CMR) through calculation of regurgitant fraction (RF) in phase contrast sequences acquired at the aortic root (as close as possible to the aortic valve). However, the impact of aortic distensibility in this evaluation remains unkown.
PURPOSE
The aim of the study was to evaluate the relation between aortic distensibility and RF valve in bicuspid aortic valve patients.
METHODS
We enrolled bicuspid aortic valve patients without significant aortic stenosis (maximum velocity <2.5 m/s) and connective tissue disease. All patients underwent a CMR study with phase contrast sequences for evaluation of regurgitant fraction at the level of the aortic valve. Aortic regurgitation was considered as mild, moderate or severe depending on RF value (mild <15%; moderate 15-30%; severe >30%). Furthermore we used cine-sequences of aortic root, ascending and proximal descending aorta to estimate aortic diameters and distensibilities, using Art Fun software. Distensibility was calculated as (change in aortic area between systole and diastole/diastolic area)/brachial pulse pressure.
RESULTS
A total of 98 bicuspid aortic valve patients were included (30% female, 49.7 ± 14.5 years). 75 (76,5%) AR was mild, 17 (17,4%) moderate and 6 (6,1%) severe. RF valvewas significantly correlated with aortic root diameter (r= 0.430 y p < 0.001 )and aortic distensibility at the level of the ascending (r = 0.273 p =0.016) and descending aorta (r = 0.502 and p< 0.001). Aortic distensibility was positively correlated with RFvalve even after adjustment for aortic diameter ( p = 0.002 and p <0.001 respectively) . (Table) (IMG)
CONCLUSIONS
In our study, aortic regurgitation in bicuspid valve patients, evaluated by CMR using RF valve, is related to aortic distensibility. Thus, aortic distensibility should be included in the evaluation of aortic regurgitation by CMR as additional parameter. However, longitudinal studies are needed to evaluate the impact of including aortic distensibility in the evaluation of AR severity by CMR.
AR SEVERITY
MILD
MODERATE
SEVERE
Descending aorta distensibility(mean ± std. deviation)
2693,68 ± 997,5
3285,8 ±1952,7
5042,99 ±2873,44
Correlation between AR severity (by RFvalve) and descending aorta distensibility
Abstract P1601 Figure.</description><issn>2047-2404</issn><issn>2047-2412</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNqNkE1OwzAQhS0EElXpAdj5AISOHSeOl6jip1IRqOo-cpxx6yokke0WldOTtsCa0UgzevPeLD5CbhncM1DpFDdb46Zb_EqZGhSmLsiIg5AJF4xf_u0grskkhC0MlYlccDYi8Z3lwOgSGx1d14aN62mF8ROxpbrz0RlauxCxDa5yjYsHqtv69-JxvfNrF09RqkPAoWtaHejsdUldSytndqF3Nd3rZo-0H4zYxnBDrqxuAk5-5pisnh5Xs5dk8fY8nz0sEiOVSkQmFNfWcsxBptIoACYzITi3oGueCYNoueRYWIBCCrRYKEyLfNBRaUzHhJ3fGt-F4NGWvXcf2h9KBuURXHkCV57BlUdwQ-bunOl2_T_s33fxc7M</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>La Mura, L</creator><creator>Teixido-Tura, G</creator><creator>Guala, A</creator><creator>Ruiz-Munoz, A</creator><creator>Lopez Sainz, A</creator><creator>Valente, F</creator><creator>Pisaniello, M</creator><creator>Strada, S</creator><creator>Granato, C</creator><creator>Galian Gay, L</creator><creator>Gonzalez-Alujas, T</creator><creator>Servato, M L</creator><creator>Ferreira, I</creator><creator>Rodriguez-Palomares, J F</creator><creator>Evangelista, A</creator><general>Oxford University Press</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20200101</creationdate><title>P1601 Relationship between aortic distensibility and aortic regurgitation assessed by CMR in bicuspid valve patients</title><author>La Mura, L ; Teixido-Tura, G ; Guala, A ; Ruiz-Munoz, A ; Lopez Sainz, A ; Valente, F ; Pisaniello, M ; Strada, S ; Granato, C ; Galian Gay, L ; Gonzalez-Alujas, T ; Servato, M L ; Ferreira, I ; Rodriguez-Palomares, J F ; Evangelista, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c799-45492aff2e60737c9001754422f0ad254ceef272e8f00874efe89e386ceee9ae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>La Mura, L</creatorcontrib><creatorcontrib>Teixido-Tura, G</creatorcontrib><creatorcontrib>Guala, A</creatorcontrib><creatorcontrib>Ruiz-Munoz, A</creatorcontrib><creatorcontrib>Lopez Sainz, A</creatorcontrib><creatorcontrib>Valente, F</creatorcontrib><creatorcontrib>Pisaniello, M</creatorcontrib><creatorcontrib>Strada, S</creatorcontrib><creatorcontrib>Granato, C</creatorcontrib><creatorcontrib>Galian Gay, L</creatorcontrib><creatorcontrib>Gonzalez-Alujas, T</creatorcontrib><creatorcontrib>Servato, M L</creatorcontrib><creatorcontrib>Ferreira, I</creatorcontrib><creatorcontrib>Rodriguez-Palomares, J F</creatorcontrib><creatorcontrib>Evangelista, A</creatorcontrib><collection>CrossRef</collection><jtitle>European heart journal cardiovascular imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>La Mura, L</au><au>Teixido-Tura, G</au><au>Guala, A</au><au>Ruiz-Munoz, A</au><au>Lopez Sainz, A</au><au>Valente, F</au><au>Pisaniello, M</au><au>Strada, S</au><au>Granato, C</au><au>Galian Gay, L</au><au>Gonzalez-Alujas, T</au><au>Servato, M L</au><au>Ferreira, I</au><au>Rodriguez-Palomares, J F</au><au>Evangelista, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>P1601 Relationship between aortic distensibility and aortic regurgitation assessed by CMR in bicuspid valve patients</atitle><jtitle>European heart journal cardiovascular imaging</jtitle><date>2020-01-01</date><risdate>2020</risdate><volume>21</volume><issue>Supplement_1</issue><issn>2047-2404</issn><eissn>2047-2412</eissn><abstract>Abstract
Funding Acknowledgements
Spanish Ministry of Economy and Competitiveness RTC-2016-5152-1, ISCIII PI17/00381, La Marató de TV3 (20151330), Eur FP7/People 267128 and CIBERCV
BACKGROUND
The severity of aortic regurgitation can be evaluated with cardiac magnetic resonance (CMR) through calculation of regurgitant fraction (RF) in phase contrast sequences acquired at the aortic root (as close as possible to the aortic valve). However, the impact of aortic distensibility in this evaluation remains unkown.
PURPOSE
The aim of the study was to evaluate the relation between aortic distensibility and RF valve in bicuspid aortic valve patients.
METHODS
We enrolled bicuspid aortic valve patients without significant aortic stenosis (maximum velocity <2.5 m/s) and connective tissue disease. All patients underwent a CMR study with phase contrast sequences for evaluation of regurgitant fraction at the level of the aortic valve. Aortic regurgitation was considered as mild, moderate or severe depending on RF value (mild <15%; moderate 15-30%; severe >30%). Furthermore we used cine-sequences of aortic root, ascending and proximal descending aorta to estimate aortic diameters and distensibilities, using Art Fun software. Distensibility was calculated as (change in aortic area between systole and diastole/diastolic area)/brachial pulse pressure.
RESULTS
A total of 98 bicuspid aortic valve patients were included (30% female, 49.7 ± 14.5 years). 75 (76,5%) AR was mild, 17 (17,4%) moderate and 6 (6,1%) severe. RF valvewas significantly correlated with aortic root diameter (r= 0.430 y p < 0.001 )and aortic distensibility at the level of the ascending (r = 0.273 p =0.016) and descending aorta (r = 0.502 and p< 0.001). Aortic distensibility was positively correlated with RFvalve even after adjustment for aortic diameter ( p = 0.002 and p <0.001 respectively) . (Table) (IMG)
CONCLUSIONS
In our study, aortic regurgitation in bicuspid valve patients, evaluated by CMR using RF valve, is related to aortic distensibility. Thus, aortic distensibility should be included in the evaluation of aortic regurgitation by CMR as additional parameter. However, longitudinal studies are needed to evaluate the impact of including aortic distensibility in the evaluation of AR severity by CMR.
AR SEVERITY
MILD
MODERATE
SEVERE
Descending aorta distensibility(mean ± std. deviation)
2693,68 ± 997,5
3285,8 ±1952,7
5042,99 ±2873,44
Correlation between AR severity (by RFvalve) and descending aorta distensibility
Abstract P1601 Figure.</abstract><pub>Oxford University Press</pub><doi>10.1093/ehjci/jez319.1019</doi></addata></record> |
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| language | eng |
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| source | Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| title | P1601 Relationship between aortic distensibility and aortic regurgitation assessed by CMR in bicuspid valve patients |
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