Remote ischemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity: results from a randomized preclinical trial in pigs

Abstract Introduction Anthracycline-induced cardiotoxicity (AIC) is a serious adverse effect occurring in a significant proportion of patients. Irreversible mitochondrial damage is a central mechanism of AIC. Despite many efforts, there is a lack of therapies able to prevent AIC. Remote ischemic pre...

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Veröffentlicht in:European heart journal 2020-11, Vol.41 (Supplement_2)
Hauptverfasser: Galan-Arriola, C, Villena-Gutierrez, R, Higuero-Verdejo, M.I, Diaz-Rengifo, I.A, Pizarro, G, Lopez, G.J, De Molina-Iracheta, A, Perez-Martinez, C, Garcia, R.D, Gonzalez-Calle, D, Sanchez, P.L, Oliver, E, Fuster, V, Sanchez-Gonzalez, J, Ibanez, B
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Sprache:eng
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