Prognostic accuracy of common heart failure scales in patients with dilated cardiomyopathy

Abstract Introduction The reliable identification of patients with heart failure (HF) and high mortality risk is crucial for treatment optimalization and prognostication, especially in younger population in dilated cardiomyopathy (DCM). However, the profile of DCM patients significantly differs from the general HF population. Therefore, the applicability of commonly used HF prognostic scales may be sub-optimal in DCM. Purpose Comparison of the prognostic accuracy of common HF prognostic scales in DCM. Methods Between 2010 and 2018 we analysed 406 DCM in- and outpatients (aged 54±14 years, 76% male, NYHA: 2.5±0.9, symptoms duration: 40±58 months, EF: 26±9%, LVEDd: 66±10mm, NT-proBNP: 3662±7617pg/ml, 10% had ICD, 3.5% had CRT). The mortality risk was assessed by 8 most popular HF prognostic scores. In 2019 information on patients status were gathered after 48±32months. Results During first month 4 patients (1.0%) died, after 1 year – 19 (6%), 2 years – 32 (11%), 3 years – 42 (18%), 4 years – 52 (27%), 5 years – 59 (40%). BCN and SHFM calculators had the best prognostic ability for 1–5 years mortality (Table 1). Conclusions Mortality risk of DCM patients during 5 years is high and reaches 40%. BCN and SHFM calculators had the best prognostic ability for 1–5 years mortality. Table 1. Prognostic performance of most common HF prognostic scales AUC 95% CI p-value In-hospital mortality risk by OPTIMIZE-HF 0.747 0.503–0.990 0.03 1-year mortality risk by MAGGIC 0.702 0.565–0.840 0.004 1-year mortality risk by SHFM 0.808 0.682–0.934