HDAC4 regulates vascular inflammation via activation of autophagy

Abstract Aims Angiotensin II (Ang II) causes vascular inflammation, leading to vascular endothelial cell dysfunction, and is associated with the development of cardiovascular diseases. Therefore, interventions in inflammation may contribute to the reduction of cardiovascular diseases. Here, we aim t...

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Veröffentlicht in:	Cardiovascular research 2018-06, Vol.114 (7), p.1016-1028
Hauptverfasser:	Yang, Di, Xiao, ChenXi, Long, Fen, Su, ZhengHua, Jia, WanWan, Qin, Ming, Huang, MengWei, Wu, WeiJun, Suguro, Rinkiko, Liu, XinHua, Zhu, YiZhun
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Angiotensin II Animals Autophagy Cells, Cultured Disease Models, Animal Forkhead Box Protein O3 - genetics Forkhead Box Protein O3 - metabolism Histone Deacetylases - genetics Histone Deacetylases - metabolism Male Mice, Inbred C57BL Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism Muscle, Smooth, Vascular - enzymology Muscle, Smooth, Vascular - pathology Myocytes, Smooth Muscle - enzymology Myocytes, Smooth Muscle - pathology Protein Processing, Post-Translational Rats Rats, Sprague-Dawley Signal Transduction Vasculitis - chemically induced Vasculitis - enzymology Vasculitis - genetics Vasculitis - pathology
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