Population Pharmacokinetics and Pharmacodynamics of Ciprofloxacin Prophylaxis in Pediatric Acute Lymphoblastic Leukemia Patients

Abstract Background Ciprofloxacin is used as antimicrobial prophylaxis in pediatric acute lymphoblastic leukemia (ALL) to decrease infections with gram-negative bacteria. However, there are no clear guidelines concerning prophylactic dose. Aims To determine the pharmacokinetics and pharmacodynamics...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Clinical infectious diseases 2020-11, Vol.71 (8), p.e281-e288
Hauptverfasser:	Sassen, S D T, Mathôt, R A A, Pieters, R, de Haas, V, Kaspers, G J L, van den Bos, C, Tissing, W J E, te Loo, D M W W, Bierings, M B, van Westreenen, M, van der Sluis, I M, Zwaan, C M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Area Under Curve Child Ciprofloxacin - pharmacology Ciprofloxacin - therapeutic use Drug Resistance, Bacterial Humans Microbial Sensitivity Tests Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Prospective Studies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!