Development of an HPLC-UV Method to Assay Empagliflozin Tablets and Identification of the Major Photoproduct by Quadrupole Time-of-Flight Mass Spectrometry

Abstract Diabetes is a set of metabolic disorders that affect >400 million individuals worldwide. Empagliflozin belongs to the gliflozin class and is used orally to treat type 2 diabetes. In this study, a simple stability-indicating HPLC-UV method was developed to assay empagliflozin tablets and...

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Veröffentlicht in:Journal of chromatographic science 2021-05, Vol.59 (6), p.526-535
Hauptverfasser: Burin, Suelen Leticia, Lourenço, Rebeca Lino, Doneda, Morgana, Müller, Edson Irineu, Paula, Fávero Reisdorfer, Adams, Andréa Inês Horn
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Sprache:eng
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