Truncation of MYH8 tail in AML: a Novel prognostic marker with increase cell migration and epithelial-mesenchymal transition utilizing RAF/MAPK pathway

MYH8 is an actin-based motor protein involved in integrin-mediated cell adhesion and migration. Heretofore, the association of MYH8 mutation and cancer is unclear. In this study, we investigated the biologic significance of novel MYH8 tail truncation mutation, R1292X in acute myeloid leukemia (AML)...

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Veröffentlicht in:	Carcinogenesis (New York) 2020-07, Vol.41 (6), p.817-827
Hauptverfasser:	Park, Hyejoo, Kim, Daeyoon, Kim, Dongchan, Park, Jihyun, Koh, Youngil, Yoon, Sung-Soo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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