Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway

TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) can selectively trigger apoptosis in various cancer cell types. However, many cancer cells are resistant to death receptor-mediated apoptosis. Combination therapy with platinum complexes may affect TRAIL-induced signaling via modulation...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Carcinogenesis (New York) 2011, Vol.32 (1), p.42-51
Hauptverfasser:	VONDALOVA BLANAROVA, Olga, JELINKOVA, Iva, HOFMANOVA, Jiřina, VEREB, György, KOZUBIK, Alois, SZÖÖR, Arpád, SKENDER, Belma, SOUCEK, Karel, HORVATH, Viktor, VACULOVA, Alena, ANDERA, Ladislav, SOVA, Petr, SZÖLLÖSI, János
Format:	Artikel
Sprache:	eng
Schlagworte:	Amantadine - analogs & derivatives Amantadine - pharmacology Apoptosis - drug effects Apoptosis - physiology Biological and medical sciences Blotting, Western Carcinogenesis, carcinogens and anticarcinogens Cell Line, Tumor Cell Separation Cisplatin - pharmacology Flow Cytometry Fluorescent Antibody Technique Humans Medical sciences Microscopy, Confocal Neoplasms - metabolism Organoplatinum Compounds - pharmacology Protein Transport - drug effects Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA Interference Signal Transduction - drug effects Signal Transduction - physiology TNF-Related Apoptosis-Inducing Ligand - metabolism Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!