SOX4 overexpression regulates the p53-mediated apoptosis in hepatocellular carcinoma: clinical implication and functional analysis in vitro

Background and aims: The underlying molecular mechanisms of hepatocellular carcinoma (HCC) remain poorly understood due to its complex development process. The human T cell-specific transcription factor sex-determining region Y-related high-mobility group (HMG) box 4 (SOX4) has been linked to develo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Carcinogenesis (New York) 2010-07, Vol.31 (7), p.1298-1307
Hauptverfasser:	Hur, Wonhee, Rhim, Hyangshuk, Jung, Chan Kwon, Kim, Jin Dong, Bae, Si Hyun, Jang, Jeong Won, Yang, Jin Mo, Oh, Seong-Taek, Kim, Dong Goo, Wang, Hee Jung, Lee, Sean Bong, Yoon, Seung Kew
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Carcinoma, Hepatocellular - etiology Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - radiotherapy Gastroenterology. Liver. Pancreas. Abdomen Hep G2 Cells Humans Liver Neoplasms - etiology Liver Neoplasms - pathology Liver Neoplasms - radiotherapy Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Promoter Regions, Genetic Protein Structure, Tertiary SOXC Transcription Factors - analysis SOXC Transcription Factors - chemistry SOXC Transcription Factors - physiology Transcriptional Activation Tumor Suppressor Protein p53 - physiology Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!