EBT: a statistic test identifying moderate size of significant features with balanced power and precision for genome-wide rate comparisons

In genome-wide rate comparison studies, there is a big challenge for effective identification of an appropriate number of significant features objectively, since traditional statistical comparisons without multi-testing correction can generate a large number of false positives while multi-testing co...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2017-09, Vol.33 (17), p.2631-2641
Hauptverfasser:	Hui, Xinjie, Hu, Yueming, Sun, Ming-An, Shu, Xingsheng, Han, Rongfei, Ge, Qinggang, Wang, Yejun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma of Lung Carcinoma, Squamous Cell - genetics Databases, Genetic Genome, Human Genomics - methods Humans Lung Neoplasms - genetics Machine Learning Mutation Sequence Analysis, DNA - methods
Online-Zugang:	Volltext
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