A phase II study of ZD0473 given as a short infusion every 3 weeks to patients with advanced or metastatic breast cancer: a National Cancer Institute of Canada Clinical Trials Group trial, IND 129

Background: ZD0473 is a new generation platinum compound with activity against a wide range of human tumor cell lines and xenografts, including carboplatin- and cisplatin-resistant lines. A phase II study of ZD0473 in advanced breast cancer was initiated by the National Cancer Institute of Canada Cl...

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Veröffentlicht in:	Annals of oncology 2003-04, Vol.14 (4), p.543-548
Hauptverfasser:	Gelmon, K. A., Vandenberg, T. A., Panasci, L., Norris, B., Crump, M., Douglas, L., Walsh, W., Matthews, S. J., Seymour, L. K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic agents Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - pathology Chemotherapy Disease Progression Female Humans Infusions, Intravenous Key words: breast cancer Medical sciences Middle Aged Neoplasm Metastasis Neutropenia - chemically induced Organoplatinum Compounds - administration & dosage Organoplatinum Compounds - adverse effects Organoplatinum Compounds - pharmacology Pharmacology. Drug treatments phase II studies platinum Treatment Outcome ZD0473
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