Atorvastatin blocks increased L-type Ca^2+ current and cell injury elicited by angiotensin II via inhibiting oxide stress

The L-type Ca^2+ current (ICa,L) plays a crucial role in shaping action potential and is involved in cardiac arrhythmia. Statins have been demonstrated to contribute to anti-apoptotic and anti-arrhythmic effects in the heart. Here, we examined whether atorvastatin regulates the ICa,L and cell injury...

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Veröffentlicht in:Acta biochimica et biophysica Sinica 2016-04, Vol.48 (4), p.378-384
Hauptverfasser: Ma, Yanzhuo, Kong, Lingfeng, Qi, Shuying, Wang, Dongmei
Format: Artikel
Sprache:eng
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