Epistasis Detection in Genome-Wide Screening for Complex Human Diseases in Structured Populations

Over the years, a more prominent role has been given to gene–gene interaction (epistasis) detection, in view of precision medicine and the hunt for novel drug targets and biomarkers for complex diseases. Acknowledging data complexity as embodied by epistasis potentially increases the power of genome...

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Veröffentlicht in:	Network and systems medicine 2019-09, Vol.2 (1), p.19-27
Hauptverfasser:	Abegaz, Fentaw, Van Lishout, François, Mahachie John, Jestinah M., Chiachoompu, Kridsadakorn, Bhardwaj, Archana, Gusareva, Elena S., Wei, Zhi, Hakonarson, Hakon, Van Steen, Kristel
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Chromosomes Consortia Crohn's disease Genes Genomes Genotype & phenotype Inflammatory bowel disease Original Research Population Software Studies
Online-Zugang:	Volltext
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