Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae

The glucose deprivation-induced release of [3H]D-aspartate was studied in bovine and human retinas in a superfusion apparatus. [3H]D-aspartate release was significantly increased upon omitting glucose in the superfusion buffer. This effect was dependent on external Ca2+ because L- and N-type Ca2+-ch...

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Veröffentlicht in:	Journal of ocular pharmacology and therapeutics 2003-12, Vol.19 (6), p.599-609
Hauptverfasser:	OHIA, Sunny E, OLUBUSAYO AWE, S, OPERE, Catherine A, LEDAY, Angela M, HARRIS, Lydia C, KULKARNI, Kaustubh, SHARIF, Najam A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine - analogs & derivatives Alanine - pharmacology Animals Biguanides - administration & dosage Biological and medical sciences Calcium Channel Blockers - pharmacology Cattle D-Aspartic Acid - antagonists & inhibitors D-Aspartic Acid - chemistry D-Aspartic Acid - metabolism Diltiazem - pharmacology Dizocilpine Maleate - pharmacology Drug Synergism Glucose - antagonists & inhibitors Glucose - deficiency Glucose - pharmacology Glutamic Acid - pharmacology Glycine - administration & dosage Glycine - analogs & derivatives Humans Kainic Acid - administration & dosage Medical sciences N-Methylaspartate - pharmacology Nitrendipine - pharmacology omega-Conotoxins - pharmacology Ophthalmology Perfusion - methods Pharmacology. Drug treatments Piperidines - administration & dosage Polyamines - antagonists & inhibitors Polyamines - pharmacology Receptors, Glutamate - drug effects Receptors, Glutamate - metabolism Retina - drug effects Retina - metabolism Tritium - chemistry Tritium - metabolism Verapamil - pharmacology
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