Staging of the Baboon Response to Group A Streptococci Administered Intramuscularly: A Descriptive Study of the Clinical Symptoms and Clinical Chemical Response Patterns

Group A streptococcal infections, ranging from necrotizing fasciitis and myositis to toxic shock syndrome, have increased over the last 10 years. We developed the first primate model of necrotizing fasciitis and myositis. Thirteen baboons were inoculated intramuscularly with group A streptococci (GA...

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Veröffentlicht in:	Clinical infectious diseases 1999-07, Vol.29 (1), p.167-177
Hauptverfasser:	Taylor, Fletcher B., Bryant, Amy E., Blick, Kenneth E., Hack, Eric, Jansen, Patty M., Kosanke, Stanley D., Stevens, Dennis L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult respiratory distress syndrome Animals Bacteremia Bacterial diseases Biological and medical sciences Blood Clinical Articles Disease models Disease Models, Animal Experimental bacterial diseases and models Fasciitis, Necrotizing - immunology Fasciitis, Necrotizing - physiopathology Female Humans Infections Infectious diseases Injections, Intramuscular Inoculation Lymphocytes Male Medical sciences Muscle tissues Myositis - immunology Myositis - physiopathology Necrotizing fasciitis Neutrophils Papio Shock, Septic - immunology Shock, Septic - physiopathology Streptococcus pyogenes - immunology Streptococcus pyogenes - pathogenicity
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